BIACORE Applications for Glycoconjugate Research.

Steric hindrance effects on surface reactions: applications to BIAcore.

Because surface-volume reactions occur in many biological and industrial processes, understanding the rate of such reactions is important. The BIAcore surface plasmon resonance (SPR) biosensor for measuring rate constants has such a geometry. Though several models of the BIAcore have been presented, few take into account that large ligand molecules can block multiple receptor sites, thus skewin...

Steric hindrance effects in thin reaction zones: applications to BIAcore

Many biological and industrial processes have reactions which occur in thin zones of densely packed receptors. Understanding the rate of such reactions is important, and the BIAcore surface plasmon resonance biosensor for measuring rate constants has such a geometry. However, interpreting biosensor data correctly is difficult since large ligand molecules can block multiple receptor sites, thus ...

Ligand fishing with Biacore

A Capacitive Fed Microstrip Patch Antenna with Air Gap for Wideband Applications (RESEARCH NOTE)

In this paper a microstrip antenna on a suspended substrate with capacitive feed is presented. capacitive feed is created by a slot within the rectangular patch around the feed point. The proposed antenna exhibits a much higher impedance bandwidth of about 47% (S11 < −10 dB). Effects of key design parameters such as the air gap between the substrate and the ground plane, the gap width between r...

Overview of molecular interactions using Biacore

Surface Plasmon Resonance (SPR) technology is a powerful tool for studying a wide range of different putative interactions. This kind of optical biosensors allow to obtain (in real time and without labelling) quantitative and qualitative information about the kinetics of the surfacebinding process. The most critical points to keep in mind when using the technique are presented, as well as pract...